Neuromodulation is an established therapy for chronic, refractory neuropathic pain (Taylor. 2006). It was first made clinically available in 1967 as a salvage therapy for chronic pain states (Shealy CN, Mortimer JT 1967; Slavin 2014). The therapy works by modulating pain pathways through the delivery of electrical current to achieve pain relief. Electrical current is supplied by electrodes located on thin wires, called electrode leads, which are positioned near target structures. Originally the dorsal column was the therapeutic target. This therapy adopted the term spinal cord stimulation (SCS). However, traditional SCS had limitations that gave rise to advanced neurostimulation techniques pursuing focal pain generators in the dorsal root ganglion.
|Original language||English (US)|
|Title of host publication||The Handbook of Neuromodulation (2 Volume Set)|
|Subtitle of host publication||Volme 1|
|Publisher||Nova Science Publishers, Inc.|
|Number of pages||16|
|State||Published - Jan 1 2022|
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