Down syndrome and Alzheimer disease: A "multi-hit" hypothesis based on multiple contributing factors resulting in pleotrophic consequences

Medicine and Dentistry

• Alzheimer's Disease 33%
• Amyloid 33%
• Cardiovascular System 33%
• Combination Therapy 33%
• Death 33%
• Degeneration 33%
• Deterioration 33%
• Development 33%
• Down Syndrome 100%
• Lesion 33%
• Mediator 33%
• Neuropathology 33%
• Oxidative Stress 33%
• Pathology 33%
• Therapeutic Procedure 33%

INIS

• death 33%
• downs syndrome 100%
• failures 33%
• foundations 33%
• hormones 33%
• hypothesis 66%
• knock-out reactions 33%
• nervous system diseases 33%
• oxidation 33%
• pathology 33%