Draft genome sequences of three β-lactam-catabolizing soil Proteobacteria

Terence Spencer Crofts*, Bin Wang, Aaron Spivak, Tara A. Gianoulis, Kevin J. Forsberg, Molly K. Gibson, Lauren A. Johnsky, Stacey M. Broomall, C. Nicole Rosenzweig, Evan W. Skowronski, Henry S. Gibbons, Morten O.A. Sommer, Gautam Dantasa

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

2 Scopus citations


Most antibiotics are derived from the soil, but their catabolism there, which is necessary to close the antibiotic carbon cycle, remains uncharacterized. We report the first draft genome sequences of soil Proteobacteria identified for subsisting solely on β-lactams as their carbon sources. The genomes encode multiple β-lactamases, although their antibiotic catabolic pathways remain enigmatic.

Original languageEnglish (US)
Article numbere00653-17
JournalGenome Announcements
Issue number32
StatePublished - Aug 1 2017

ASJC Scopus subject areas

  • Molecular Biology
  • Genetics

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