Dramatic enhancement in pH sensitivity and signal intensity through ligand modification of a dicobalt PARACEST probe

Agnes E. Thorarinsdottir, T. David Harris*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

5 Scopus citations

Abstract

The employment of an ancillary amine-substituted bisphosphonate ligand affords a dicobalt complex able to quantitate pH with a remarkably high sensitivity of 8.8(5) pH unit−1 at 37 °C through a ratiometric paramagnetic chemical exchange saturation transfer (PARACEST) approach, where the different pH dependences of amine and amide CEST peak intensities are utilized.

Original languageEnglish (US)
Pages (from-to)794-797
Number of pages4
JournalChemical Communications
Volume55
Issue number6
DOIs
StatePublished - Jan 1 2019

ASJC Scopus subject areas

  • Catalysis
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Chemistry(all)
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry

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