Abstract
Asplenia was suspected in one patient with combined immunodeficiency syndrome and 5 with congenital cardiac anomalies who had Howell-Jolly bodies on peripheral blood smears. 99mTc-sulfur colloid scans were equivocal for absence of the spleen. When they were compared with the 99mTc-PIPIDA hepatobiliary images, a discrepancy in organ morphology between the two scans indicated that the spleen was present, whereas similarity of the two images suggested asplenia. This procedure was useful in establishing asplenia in 4 patients and confirming the presence of a rudimentary or ectopic spleen in 2 others. Unequivocal demonstration of the spleen on the sulfur colloid scans makes the hepatobiliary study unnecessary, while unequivocal demonstration of a normal-appearing liver without splenic activity may warrant a tagged red-cell study for a more complete evaluation.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 805-810 |
| Number of pages | 6 |
| Journal | Radiology |
| Volume | 145 |
| Issue number | 3 |
| DOIs | |
| State | Published - Jan 1 1982 |
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ASJC Scopus subject areas
- Radiology Nuclear Medicine and imaging
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Dual radiopharmaceutical imaging in congenital asplenia syndrome. / Rao, B. K.; Shore, R. M.; Lieberman, L. M.; Polcyn, R. E.
In: Radiology, Vol. 145, No. 3, 01.01.1982, p. 805-810.Research output: Contribution to journal › Article
TY - JOUR
T1 - Dual radiopharmaceutical imaging in congenital asplenia syndrome.
AU - Rao, B. K.
AU - Shore, R. M.
AU - Lieberman, L. M.
AU - Polcyn, R. E.
PY - 1982/1/1
Y1 - 1982/1/1
N2 - Asplenia was suspected in one patient with combined immunodeficiency syndrome and 5 with congenital cardiac anomalies who had Howell-Jolly bodies on peripheral blood smears. 99mTc-sulfur colloid scans were equivocal for absence of the spleen. When they were compared with the 99mTc-PIPIDA hepatobiliary images, a discrepancy in organ morphology between the two scans indicated that the spleen was present, whereas similarity of the two images suggested asplenia. This procedure was useful in establishing asplenia in 4 patients and confirming the presence of a rudimentary or ectopic spleen in 2 others. Unequivocal demonstration of the spleen on the sulfur colloid scans makes the hepatobiliary study unnecessary, while unequivocal demonstration of a normal-appearing liver without splenic activity may warrant a tagged red-cell study for a more complete evaluation.
AB - Asplenia was suspected in one patient with combined immunodeficiency syndrome and 5 with congenital cardiac anomalies who had Howell-Jolly bodies on peripheral blood smears. 99mTc-sulfur colloid scans were equivocal for absence of the spleen. When they were compared with the 99mTc-PIPIDA hepatobiliary images, a discrepancy in organ morphology between the two scans indicated that the spleen was present, whereas similarity of the two images suggested asplenia. This procedure was useful in establishing asplenia in 4 patients and confirming the presence of a rudimentary or ectopic spleen in 2 others. Unequivocal demonstration of the spleen on the sulfur colloid scans makes the hepatobiliary study unnecessary, while unequivocal demonstration of a normal-appearing liver without splenic activity may warrant a tagged red-cell study for a more complete evaluation.
UR - http://www.scopus.com/inward/record.url?scp=0020344795&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0020344795&partnerID=8YFLogxK
U2 - 10.1148/radiology.145.3.7146415
DO - 10.1148/radiology.145.3.7146415
M3 - Article
C2 - 7146415
AN - SCOPUS:0020344795
VL - 145
SP - 805
EP - 810
JO - Radiology
JF - Radiology
SN - 0033-8419
IS - 3
ER -