Duration of anticoagulation after cerebral venous sinus thrombosis

Frances Caprio, Richard A. Bernstein*

*Corresponding author for this work

Research output: Contribution to journalReview article

12 Scopus citations

Abstract

Cerebral venous sinus thrombosis (CVST) often occurs in young patients and is treated with acute and then long-term oral anticoagulation. It is important to decide when to discontinue anticoagulation, as lifelong anticoagulation exposes the patient to considerable cumulative risk. However, a lack of high quality studies makes choosing a duration of anticoagulation after CVST difficult. In this article, we review the evidence for different treatment durations in several common clinical scenarios of CVST. In addition, when no direct evidence is available, we discuss and extrapolate from the more comprehensively studied situation of systemic venous thromboembolic disease. Recommendations are graded using standard criteria for the level of evidence.

Original languageEnglish (US)
Pages (from-to)335-342
Number of pages8
JournalNeurocritical Care
Volume16
Issue number2
DOIs
StatePublished - Apr 1 2012

Keywords

  • Cerebral venous sinus thrombosis
  • Duration
  • Oral anticoagulation
  • Recurrence
  • Venous thromboembolis

ASJC Scopus subject areas

  • Clinical Neurology
  • Critical Care and Intensive Care Medicine

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