Dynamic Docking

Judith M. Nocek, Brian M Hoffman

Research output: Chapter in Book/Report/Conference proceedingEntry for encyclopedia/dictionary


Dynamic docking (DD) denotes a complex formed between reactive (electron transfer (ET)-active) protein partners in which a large ensemble of weakly-bound configurations of the complex contribute to binding, but only a few are reactive. Typically, the ET reaction occurs within the “thermodynamic” or “fast exchange” limit, in which case binding is effectively decoupled from reactivity, and it is possible to modulate reactivity without changing affinity.
Original languageEnglish (US)
Title of host publicationEncyclopedia of Biophysics
EditorsGordon C K Roberts
PublisherSpringer Berlin Heidelberg
Number of pages4
ISBN (Electronic)978-3-642-16712-6
ISBN (Print)978-3-642-16711-9
StatePublished - 2013


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