| Original language | English (US) |
|---|---|
| Title of host publication | Encyclopedia of Biophysics |
| Editors | Gordon C K Roberts |
| Publisher | Springer Berlin Heidelberg |
| Pages | 534-537 |
| Number of pages | 4 |
| ISBN (Electronic) | 978-3-642-16712-6 |
| ISBN (Print) | 978-3-642-16711-9 |
| State | Published - 2013 |
Abstract
Dynamic docking (DD) denotes a complex formed between reactive (electron transfer (ET)-active) protein partners in which a large ensemble of weakly-bound configurations of the complex contribute to binding, but only a few are reactive. Typically, the ET reaction occurs within the “thermodynamic” or “fast exchange” limit, in which case binding is effectively decoupled from reactivity, and it is possible to modulate reactivity without changing affinity.