Dynamic loads are determinants of peak bone mass

Kirsten C. Moisio, Debra E. Hurwitz, Dale R. Sumner*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

26 Scopus citations


This study investigated the association between non-invasive measurements of bone mass and markers of dynamic and static hip joint loads in subjects expected to be at peak bone mass. The bone mineral density (BMD) and bone mineral content (BMC) of three proximal femoral sites (neck, greater trochanter, and total) were measured by dual energy X-ray absorptiometry, and the peak external joint moments at the hip during walking and jogging were calculated from gait analyses of 31 normal human subjects ranging in age from 30 to 49 years (18 females, 13 males). Various multiple regression analyses were performed to determine how much of the variance in BMD and BMC was explained by height, body mass, and the peak hip joint moments. In total, the models explained up to 40% of the variance in BMD and 58% of the variance in BMC. Inclusion of height or body mass did not increase the explanatory power of the models for BMD and explained no more than 8% of the total variance in BMC once the joint moments from walking were allowed to enter the models. These data support the hypothesis that variance in peak bone mass is associated with variance in dynamic hip loads largely independent of the effect of static factors such as height and body mass.

Original languageEnglish (US)
Pages (from-to)339-345
Number of pages7
JournalJournal of Orthopaedic Research
Issue number2
StatePublished - 2004


  • Biomechanics
  • Bone mineral density
  • DXA
  • Gait analysis
  • Hip

ASJC Scopus subject areas

  • Orthopedics and Sports Medicine


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