Dynamic Multivalent Lactosides Displayed on Cyclodextrin Beads Dangling from Polymer Strings

Alshakim Nelson, J. Fraser Stoddart*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

50 Scopus citations

Abstract

(Matrix presented) Lactose-appended cyclodextrin derivatives have been synthesized and threaded onto hydrophobic polymers in aqueous solution to form dynamic multivalent lactosides for binding to lectins. The threading process, which proceeds quickly, can be observed by one- and two- dimensional NMR spectroscopies.

Original languageEnglish (US)
Pages (from-to)3783-3786
Number of pages4
JournalOrganic Letters
Volume5
Issue number21
DOIs
StatePublished - Oct 16 2003

ASJC Scopus subject areas

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry

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