Dynamic Multivalent Lactosides Displayed on Cyclodextrin Beads Dangling from Polymer Strings

Alshakim Nelson; J. Fraser Stoddart

doi:10.1021/ol0353464

Dynamic Multivalent Lactosides Displayed on Cyclodextrin Beads Dangling from Polymer Strings

Alshakim Nelson, J. Fraser Stoddart^*

^*Corresponding author for this work

Chemistry

Research output: Contribution to journal › Article › peer-review

49 Scopus citations

Abstract

(Matrix presented) Lactose-appended cyclodextrin derivatives have been synthesized and threaded onto hydrophobic polymers in aqueous solution to form dynamic multivalent lactosides for binding to lectins. The threading process, which proceeds quickly, can be observed by one- and two- dimensional NMR spectroscopies.

Original language	English (US)
Pages (from-to)	3783-3786
Number of pages	4
Journal	Organic Letters
Volume	5
Issue number	21
DOIs	https://doi.org/10.1021/ol0353464
State	Published - Oct 16 2003

ASJC Scopus subject areas

Biochemistry
Physical and Theoretical Chemistry
Organic Chemistry

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10.1021/ol0353464

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title = "Dynamic Multivalent Lactosides Displayed on Cyclodextrin Beads Dangling from Polymer Strings",

abstract = "(Matrix presented) Lactose-appended cyclodextrin derivatives have been synthesized and threaded onto hydrophobic polymers in aqueous solution to form dynamic multivalent lactosides for binding to lectins. The threading process, which proceeds quickly, can be observed by one- and two- dimensional NMR spectroscopies.",

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