Dynamic Multivalent Lactosides Displayed on Cyclodextrin Beads Dangling from Polymer Strings

Alshakim Nelson; J. Fraser Stoddart

doi:10.1021/ol0353464

Dynamic Multivalent Lactosides Displayed on Cyclodextrin Beads Dangling from Polymer Strings

Alshakim Nelson, J. Fraser Stoddart^*

^*Corresponding author for this work

Chemistry

Research output: Contribution to journal › Article › peer-review

52 Scopus citations

Abstract

(Matrix presented) Lactose-appended cyclodextrin derivatives have been synthesized and threaded onto hydrophobic polymers in aqueous solution to form dynamic multivalent lactosides for binding to lectins. The threading process, which proceeds quickly, can be observed by one- and two- dimensional NMR spectroscopies.

Original language	English (US)
Pages (from-to)	3783-3786
Number of pages	4
Journal	Organic Letters
Volume	5
Issue number	21
DOIs	https://doi.org/10.1021/ol0353464
State	Published - Oct 16 2003

ASJC Scopus subject areas

Biochemistry
Physical and Theoretical Chemistry
Organic Chemistry

Access to Document

10.1021/ol0353464

Cite this

@article{3e25bfe0773f443a98dee24be63d1030,

title = "Dynamic Multivalent Lactosides Displayed on Cyclodextrin Beads Dangling from Polymer Strings",

abstract = "(Matrix presented) Lactose-appended cyclodextrin derivatives have been synthesized and threaded onto hydrophobic polymers in aqueous solution to form dynamic multivalent lactosides for binding to lectins. The threading process, which proceeds quickly, can be observed by one- and two- dimensional NMR spectroscopies.",

author = "Alshakim Nelson and Stoddart, {J. Fraser}",

year = "2003",

month = oct,

day = "16",

doi = "10.1021/ol0353464",

language = "English (US)",

volume = "5",

pages = "3783--3786",

journal = "Organic Letters",

issn = "1523-7060",

publisher = "American Chemical Society",

number = "21",

}

TY - JOUR

T1 - Dynamic Multivalent Lactosides Displayed on Cyclodextrin Beads Dangling from Polymer Strings

AU - Nelson, Alshakim

AU - Stoddart, J. Fraser

PY - 2003/10/16

Y1 - 2003/10/16

N2 - (Matrix presented) Lactose-appended cyclodextrin derivatives have been synthesized and threaded onto hydrophobic polymers in aqueous solution to form dynamic multivalent lactosides for binding to lectins. The threading process, which proceeds quickly, can be observed by one- and two- dimensional NMR spectroscopies.

AB - (Matrix presented) Lactose-appended cyclodextrin derivatives have been synthesized and threaded onto hydrophobic polymers in aqueous solution to form dynamic multivalent lactosides for binding to lectins. The threading process, which proceeds quickly, can be observed by one- and two- dimensional NMR spectroscopies.

UR - http://www.scopus.com/inward/record.url?scp=0242712912&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0242712912&partnerID=8YFLogxK

U2 - 10.1021/ol0353464

DO - 10.1021/ol0353464

M3 - Article

C2 - 14535709

AN - SCOPUS:0242712912

VL - 5

SP - 3783

EP - 3786

JO - Organic Letters

JF - Organic Letters

SN - 1523-7060

IS - 21

ER -

Dynamic Multivalent Lactosides Displayed on Cyclodextrin Beads Dangling from Polymer Strings

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this