TY - JOUR
T1 - Dynamics and efficiency of DNA hole transport via alternating AT versus poIy(A) sequences
AU - Lewis, Frederick D.
AU - Daublain, Pierre
AU - Cohen, Boiko
AU - Vura-Weis, Josh
AU - Shafirovich, Vladimir
AU - Wasielewski, Michael R.
PY - 2007/12/12
Y1 - 2007/12/12
N2 - The dynamics and efficiencies of photoinduced charge separation across alternating AT, ATA, ATAT, and ATATA base pair sequences in synthetic DNA hairpins have been determined by means of femtosecond time-resolved transient absorption spectroscopy. When compared to our results for charge transport across poly(A) sequences, both the rate constants and efficiencies are lower for the poly(AT) sequences, especially at short distances (3 or 4 base pairs). At longer distances, charge separation becomes weakly distance-dependent for poly(AT) as well as poly(A) sequences. Both the poly(AT) and poly(A) sequences undergo charge separation via a multistep mechanism consisting of photochemical hole injection into the neighboring A followed by hole transport and hole trapping.
AB - The dynamics and efficiencies of photoinduced charge separation across alternating AT, ATA, ATAT, and ATATA base pair sequences in synthetic DNA hairpins have been determined by means of femtosecond time-resolved transient absorption spectroscopy. When compared to our results for charge transport across poly(A) sequences, both the rate constants and efficiencies are lower for the poly(AT) sequences, especially at short distances (3 or 4 base pairs). At longer distances, charge separation becomes weakly distance-dependent for poly(AT) as well as poly(A) sequences. Both the poly(AT) and poly(A) sequences undergo charge separation via a multistep mechanism consisting of photochemical hole injection into the neighboring A followed by hole transport and hole trapping.
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U2 - 10.1021/ja076876o
DO - 10.1021/ja076876o
M3 - Article
C2 - 18020341
AN - SCOPUS:37049002254
VL - 129
SP - 15130
EP - 15131
JO - Journal of the American Chemical Society
JF - Journal of the American Chemical Society
SN - 0002-7863
IS - 49
ER -