Dynamics of Gel Electrophoresis

Edward O. Shaffer; Monica Olvera De La Cruz

doi:10.1021/ma00193a057

Dynamics of Gel Electrophoresis

Edward O. Shaffer, Monica Olvera De La Cruz^*

^*Corresponding author for this work

Materials Science and Engineering

Research output: Contribution to journal › Article › peer-review

50 Scopus citations

Abstract

An off-lattice computer simulation based on the Langevin equation of motion is used to study gel electrophoresis. The simulated chain dynamics are dramatically different from the dynamics predicted by tube-reptation theories. The mobility of different length chains is traced, showing the loss of length dependence as the field is increased. The dynamics of the chain in the field-independent mobility regime are illustrated.

Original language	English (US)
Pages (from-to)	1351-1355
Number of pages	5
Journal	Macromolecules
Volume	22
Issue number	3
DOIs	https://doi.org/10.1021/ma00193a057
State	Published - May 1 1989

ASJC Scopus subject areas

Organic Chemistry
Polymers and Plastics
Inorganic Chemistry
Materials Chemistry

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10.1021/ma00193a057

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title = "Dynamics of Gel Electrophoresis",

abstract = "An off-lattice computer simulation based on the Langevin equation of motion is used to study gel electrophoresis. The simulated chain dynamics are dramatically different from the dynamics predicted by tube-reptation theories. The mobility of different length chains is traced, showing the loss of length dependence as the field is increased. The dynamics of the chain in the field-independent mobility regime are illustrated.",

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AB - An off-lattice computer simulation based on the Langevin equation of motion is used to study gel electrophoresis. The simulated chain dynamics are dramatically different from the dynamics predicted by tube-reptation theories. The mobility of different length chains is traced, showing the loss of length dependence as the field is increased. The dynamics of the chain in the field-independent mobility regime are illustrated.

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Dynamics of Gel Electrophoresis

Abstract

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