Dynamics of soft nanomaterials captured by transmission electron microscopy in liquid water

Maria T. Proetto, Anthony M. Rush, Miao Ping Chien, Patricia Abellan Baeza, Joseph P. Patterson, Matthew P. Thompson, Norman H. Olson, Curtis E. Moore, Arnold L. Rheingold, Christopher Andolina, Jill Millstone, Stephen B. Howell, Nigel D. Browning, James E. Evans, Nathan C. Gianneschi*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

87 Scopus citations


In this paper we present in situ transmission electron microscopy of synthetic polymeric nanoparticles with emphasis on capturing motion in a solvated, aqueous state. The nanoparticles studied were obtained from the direct polymerization of a Pt(II)-containing monomer. The resulting structures provided sufficient contrast for facile imaging in situ. We contend that this technique will quickly become essential in the characterization of analogous systems, especially where dynamics are of interest in the solvated state. We describe the preparation of the synthetic micellar nanoparticles together with their characterization and motion in liquid water with comparison to conventional electron microscopy analyses.

Original languageEnglish (US)
Pages (from-to)1162-1165
Number of pages4
JournalJournal of the American Chemical Society
Issue number4
StatePublished - Jan 29 2014

ASJC Scopus subject areas

  • Chemistry(all)
  • Biochemistry
  • Catalysis
  • Colloid and Surface Chemistry


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