Early Bioprosthetic Valve Failure: Mechanistic Insights via Correlation between Echocardiographic and Operative Findings

Paul C. Cremer; L. Leonardo Rodriguez; Brian P. Griffin; Carmela D. Tan; E. Rene Rodriguez; Douglas R. Johnston; Gosta B. Pettersson; Venu Menon

doi:10.1016/j.echo.2015.07.003

Early Bioprosthetic Valve Failure: Mechanistic Insights via Correlation between Echocardiographic and Operative Findings

Paul C. Cremer, L. Leonardo Rodriguez, Brian P. Griffin, Carmela D. Tan, E. Rene Rodriguez, Douglas R. Johnston, Gosta B. Pettersson, Venu Menon^*

^*Corresponding author for this work

Surgery, Cardiac Surgery Division

Research output: Contribution to journal › Review article › peer-review

24 Scopus citations

Abstract

Bioprosthetic valves are increasingly implanted, with generally consistent and durable results. Early bioprosthetic valve failure is uncommon, and most clinicians are unfamiliar with the spectrum of early structural complications involving bioprostheses. In this review, the authors organize causes of early bioprosthetic valve failure according to possible pathogenesis, demonstrate the correlation between echocardiographic and anatomic findings, and discuss potential treatments. First, they address early bioprosthetic valve stenosis secondary to thrombosis. Next, they discuss excessive pannus formation, a hitherto rarely described cause of early bioprosthetic valve failure. Finally, the authors address early structural valve deterioration mediated by calcification or primary tears. Illustrative examples with relevant echocardiographic and operative findings are provided.

Original language	English (US)
Pages (from-to)	1131-1148
Number of pages	18
Journal	Journal of the American Society of Echocardiography
Volume	28
Issue number	10
DOIs	https://doi.org/10.1016/j.echo.2015.07.003
State	Published - Oct 2015

Keywords

Bioprosthetic valve
Calcification
Pannus
Primary leaflet tear
Structural valve deterioration
Thrombus

ASJC Scopus subject areas

Radiology Nuclear Medicine and imaging
Cardiology and Cardiovascular Medicine

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10.1016/j.echo.2015.07.003

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Cremer, P. C., Rodriguez, L. L., Griffin, B. P., Tan, C. D., Rodriguez, E. R., Johnston, D. R., Pettersson, G. B., & Menon, V. (2015). Early Bioprosthetic Valve Failure: Mechanistic Insights via Correlation between Echocardiographic and Operative Findings. Journal of the American Society of Echocardiography, 28(10), 1131-1148. https://doi.org/10.1016/j.echo.2015.07.003

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title = "Early Bioprosthetic Valve Failure: Mechanistic Insights via Correlation between Echocardiographic and Operative Findings",

abstract = "Bioprosthetic valves are increasingly implanted, with generally consistent and durable results. Early bioprosthetic valve failure is uncommon, and most clinicians are unfamiliar with the spectrum of early structural complications involving bioprostheses. In this review, the authors organize causes of early bioprosthetic valve failure according to possible pathogenesis, demonstrate the correlation between echocardiographic and anatomic findings, and discuss potential treatments. First, they address early bioprosthetic valve stenosis secondary to thrombosis. Next, they discuss excessive pannus formation, a hitherto rarely described cause of early bioprosthetic valve failure. Finally, the authors address early structural valve deterioration mediated by calcification or primary tears. Illustrative examples with relevant echocardiographic and operative findings are provided.",

keywords = "Bioprosthetic valve, Calcification, Pannus, Primary leaflet tear, Structural valve deterioration, Thrombus",

author = "Cremer, {Paul C.} and Rodriguez, {L. Leonardo} and Griffin, {Brian P.} and Tan, {Carmela D.} and Rodriguez, {E. Rene} and Johnston, {Douglas R.} and Pettersson, {Gosta B.} and Venu Menon",

note = "Publisher Copyright: {\textcopyright} 2015 American Society of Echocardiography.",

year = "2015",

month = oct,

doi = "10.1016/j.echo.2015.07.003",

language = "English (US)",

volume = "28",

pages = "1131--1148",

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T1 - Early Bioprosthetic Valve Failure

T2 - Mechanistic Insights via Correlation between Echocardiographic and Operative Findings

AU - Cremer, Paul C.

AU - Rodriguez, L. Leonardo

AU - Griffin, Brian P.

AU - Tan, Carmela D.

AU - Rodriguez, E. Rene

AU - Johnston, Douglas R.

AU - Pettersson, Gosta B.

AU - Menon, Venu

PY - 2015/10

Y1 - 2015/10

N2 - Bioprosthetic valves are increasingly implanted, with generally consistent and durable results. Early bioprosthetic valve failure is uncommon, and most clinicians are unfamiliar with the spectrum of early structural complications involving bioprostheses. In this review, the authors organize causes of early bioprosthetic valve failure according to possible pathogenesis, demonstrate the correlation between echocardiographic and anatomic findings, and discuss potential treatments. First, they address early bioprosthetic valve stenosis secondary to thrombosis. Next, they discuss excessive pannus formation, a hitherto rarely described cause of early bioprosthetic valve failure. Finally, the authors address early structural valve deterioration mediated by calcification or primary tears. Illustrative examples with relevant echocardiographic and operative findings are provided.

AB - Bioprosthetic valves are increasingly implanted, with generally consistent and durable results. Early bioprosthetic valve failure is uncommon, and most clinicians are unfamiliar with the spectrum of early structural complications involving bioprostheses. In this review, the authors organize causes of early bioprosthetic valve failure according to possible pathogenesis, demonstrate the correlation between echocardiographic and anatomic findings, and discuss potential treatments. First, they address early bioprosthetic valve stenosis secondary to thrombosis. Next, they discuss excessive pannus formation, a hitherto rarely described cause of early bioprosthetic valve failure. Finally, the authors address early structural valve deterioration mediated by calcification or primary tears. Illustrative examples with relevant echocardiographic and operative findings are provided.

KW - Bioprosthetic valve

KW - Calcification

KW - Pannus

KW - Primary leaflet tear

KW - Structural valve deterioration

KW - Thrombus

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DO - 10.1016/j.echo.2015.07.003

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SN - 0894-7317

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JO - Journal of the American Society of Echocardiography

JF - Journal of the American Society of Echocardiography

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ER -

Early Bioprosthetic Valve Failure: Mechanistic Insights via Correlation between Echocardiographic and Operative Findings

Abstract

Keywords

ASJC Scopus subject areas

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