TY - JOUR
T1 - Early DNA damage detection and cellular autophagy as drivers of stress-adaptive H2S production
T2 - A paradox resolved
AU - Hine, Christopher
AU - Wainwright, Derek A.
AU - Lathia, Justin D.
N1 - Publisher Copyright:
© 2021 Elsevier Ltd
PY - 2021/12/16
Y1 - 2021/12/16
N2 - Appropriately responding and adapting to genotoxic, oxidative, and metabolic stress is essential for survival and is at the heart of maintaining homeostasis. In this issue of Cell Chemical Biology, Jiang et al. (2021) describe an autophagy-dependent mechanism for cytoprotective H2S generation initiated by DNA damage and other small molecule treatments.
AB - Appropriately responding and adapting to genotoxic, oxidative, and metabolic stress is essential for survival and is at the heart of maintaining homeostasis. In this issue of Cell Chemical Biology, Jiang et al. (2021) describe an autophagy-dependent mechanism for cytoprotective H2S generation initiated by DNA damage and other small molecule treatments.
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U2 - 10.1016/j.chembiol.2021.11.007
DO - 10.1016/j.chembiol.2021.11.007
M3 - Article
C2 - 34919842
AN - SCOPUS:85121230423
VL - 28
SP - 1665
EP - 1668
JO - Cell Chemical Biology
JF - Cell Chemical Biology
SN - 2451-9448
IS - 12
ER -