Early Outcomes With HeartWare HVAD as Bridge to Transplant in Children: A Single Institution Experience

Giuseppe Ferro; Raghav Murthy; Derek Williams; Vinod A. Sebastian; Joseph M. Forbess; Kristine J. Guleserian

doi:10.1111/aor.12637

Early Outcomes With HeartWare HVAD as Bridge to Transplant in Children: A Single Institution Experience

Giuseppe Ferro^*, Raghav Murthy, Derek Williams, Vinod A. Sebastian, Joseph M. Forbess, Kristine J. Guleserian

^*Corresponding author for this work

Surgery, Cardiac Surgery Division

Research output: Contribution to journal › Article › peer-review

17 Scopus citations

Abstract

The HeartWare HVAD has been used as a bridge to cardiac transplantation in the pediatric population. We describe outcomes following HeartWare HVAD implantation at a single center. A retrospective chart review was performed of all HeartWare HVAD implants performed at our institution between May 2013 and March 2015. Eight children between the ages of 9 and 17 years underwent HVAD implantation as a bridge to transplant (N=7 cardiomyopathy, N=1 complex single ventricle). There was one operative death in the complex single ventricle patient. Seven patients (87%) were successfully bridged to transplant. Median time of support was 24.5 days (range, 6-91 days). All transplanted patients are alive and well at a median follow-up of 448 days. Our results demonstrated that mechanical support with HeartWare HVAD is feasible in patients of varying sizes (from older children to adolescents).

Original language	English (US)
Pages (from-to)	85-89
Number of pages	5
Journal	Artificial organs
Volume	40
Issue number	1
DOIs	https://doi.org/10.1111/aor.12637
State	Published - Jan 1 2016

Keywords

Cardiac transplantation
Heart failure
Pediatric
Ventricular assist device

ASJC Scopus subject areas

Bioengineering
Biomedical Engineering
Medicine (miscellaneous)
Biomaterials

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10.1111/aor.12637

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title = "Early Outcomes With HeartWare HVAD as Bridge to Transplant in Children: A Single Institution Experience",

abstract = "The HeartWare HVAD has been used as a bridge to cardiac transplantation in the pediatric population. We describe outcomes following HeartWare HVAD implantation at a single center. A retrospective chart review was performed of all HeartWare HVAD implants performed at our institution between May 2013 and March 2015. Eight children between the ages of 9 and 17 years underwent HVAD implantation as a bridge to transplant (N=7 cardiomyopathy, N=1 complex single ventricle). There was one operative death in the complex single ventricle patient. Seven patients (87%) were successfully bridged to transplant. Median time of support was 24.5 days (range, 6-91 days). All transplanted patients are alive and well at a median follow-up of 448 days. Our results demonstrated that mechanical support with HeartWare HVAD is feasible in patients of varying sizes (from older children to adolescents).",

keywords = "Cardiac transplantation, Heart failure, Pediatric, Ventricular assist device",

author = "Giuseppe Ferro and Raghav Murthy and Derek Williams and Sebastian, {Vinod A.} and Forbess, {Joseph M.} and Guleserian, {Kristine J.}",

note = "Publisher Copyright: {\textcopyright} 2016 Wiley Periodicals, Inc. and International Center for Artificial Organs and Transplantation.",

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T2 - A Single Institution Experience

AU - Ferro, Giuseppe

AU - Murthy, Raghav

AU - Williams, Derek

AU - Sebastian, Vinod A.

AU - Forbess, Joseph M.

AU - Guleserian, Kristine J.

PY - 2016/1/1

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N2 - The HeartWare HVAD has been used as a bridge to cardiac transplantation in the pediatric population. We describe outcomes following HeartWare HVAD implantation at a single center. A retrospective chart review was performed of all HeartWare HVAD implants performed at our institution between May 2013 and March 2015. Eight children between the ages of 9 and 17 years underwent HVAD implantation as a bridge to transplant (N=7 cardiomyopathy, N=1 complex single ventricle). There was one operative death in the complex single ventricle patient. Seven patients (87%) were successfully bridged to transplant. Median time of support was 24.5 days (range, 6-91 days). All transplanted patients are alive and well at a median follow-up of 448 days. Our results demonstrated that mechanical support with HeartWare HVAD is feasible in patients of varying sizes (from older children to adolescents).

AB - The HeartWare HVAD has been used as a bridge to cardiac transplantation in the pediatric population. We describe outcomes following HeartWare HVAD implantation at a single center. A retrospective chart review was performed of all HeartWare HVAD implants performed at our institution between May 2013 and March 2015. Eight children between the ages of 9 and 17 years underwent HVAD implantation as a bridge to transplant (N=7 cardiomyopathy, N=1 complex single ventricle). There was one operative death in the complex single ventricle patient. Seven patients (87%) were successfully bridged to transplant. Median time of support was 24.5 days (range, 6-91 days). All transplanted patients are alive and well at a median follow-up of 448 days. Our results demonstrated that mechanical support with HeartWare HVAD is feasible in patients of varying sizes (from older children to adolescents).

KW - Cardiac transplantation

KW - Heart failure

KW - Pediatric

KW - Ventricular assist device

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Early Outcomes With HeartWare HVAD as Bridge to Transplant in Children: A Single Institution Experience

Abstract

Keywords

ASJC Scopus subject areas

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