Early postoperative outcomes in a series of infants with hypoplastic left heart syndrome undergoing stage I palliation operation with either modified Blalock-Taussig shunt or right ventricle to pulmonary artery conduit

Clifford L. Cua*, Ravi R. Thiagarajan, Kimberlee Gauvreau, Lillian Lai, John M. Costello, David L. Wessel, Pedro J. Del Nido, John E. Mayer, Jane W. Newburger, Peter C. Laussen

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

69 Scopus citations

Abstract

Objective: Previous publications using nonconcurrent series of patients indicate improved survival for patients with hypoplastic left heart syndrome (HLHS) undergoing stage I palliation with a right ventricle to pulmonary artery conduit (NW-RVPA) vs. a modified Blalock-Taussig shunt (NW-BT). We compared postoperative outcomes in a concurrent series of patients with HLHS undergoing an NW-BT procedure vs. NW-RVPA procedure. Design: Perioperative data from 66 consecutive patients who underwent NW-BT (n = 37) or NW-RVPA (n = 29) procedures were retrospectively analyzed. Setting: Cardiac intensive care unit in a tertiary pediatric hospital. Patients: Charts were reviewed for all patients with the diagnosis of HLHS undergoing the NW-BT or NW-RVPA procedure between January 2002 and December 2003. Results: Cardiopulmonary bypass time was longer in the NW-BT group than in the NW-RVPA group (152.5 ± 52.0 vs. 134.5 ± 36.1 mins; p = .04). Postoperative diastolic pressures were higher and the PaO2 to FIO2 ratio profiles were lower for the NW-RVPA group over the first 72 hrs. Time to sternal closure (2 [1-6] vs. 4 [2-41] days; p = .01), duration of mechanical ventilation (113 [49-386] vs. 136 [84-764] hrs; p = .01), time to establish enteral feeds (4 [2-8] vs. 5 [3-22] days; p = .01), length of intensive care unit stay (11 [7-55] vs. 15 [8-90] days; p = .04), and length of hospital stay (16 [11-67] vs. 27 [12-126] days; p = .01) were shorter in the NW-RVPA group. Postoperative mortality was not significantly different between the NW-RVPA group (7%) and NW-BT group (11%). Conclusion: At an experienced institution with low stage I palliation mortality for HLHS, there were no differences in early morbidity and mortality between the NW-RVPA and NW-BT procedures. The primary advantage of the NW-RVPA procedure may be faster recovery following surgery and earlier discharge from the hospital.

Original languageEnglish (US)
Pages (from-to)238-244
Number of pages7
JournalPediatric Critical Care Medicine
Volume7
Issue number3
DOIs
StatePublished - May 2006

Keywords

  • Congenital heart disease
  • Hypoplastic left heart syndrome
  • Norwood operation

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Critical Care and Intensive Care Medicine

Fingerprint Dive into the research topics of 'Early postoperative outcomes in a series of infants with hypoplastic left heart syndrome undergoing stage I palliation operation with either modified Blalock-Taussig shunt or right ventricle to pulmonary artery conduit'. Together they form a unique fingerprint.

Cite this