Abstract
Objectives To determine the extent to which non-Latina White and African-American mother’s gestational age is associated with extremely early (<30 weeks), modestly early (30–33 weeks), and late (34–36 weeks) infant preterm birth (PTB) rates. Methods Race-specific stratified and multivariable logistic regression analyses were performed on the Illinois Transgenerational Birth File of non-Latino White and African-American infants (born 1989–1991) and their mothers (born 1956–1976). Results White mothers (n = 184) born at <30 weeks had a greater extremely early infant PTB rate than White mothers (n = 131,980) born at term: 1.6 versus 0.5%, respectively; RR = 3.6 (1.2, 11.0). African-American mothers (n = 269) born at <30 weeks had a greater extremely early infant PTB rate than African-American mothers (n = 34,885) born at term: 4.1 versus 2.1%, respectively; RR = 2.0 (1.1, 3.6). In logistic regression models the adjusted (controlling for maternal age, education, parity, prenatal care, marital status, and cigarette smoking) OR of extremely early PTB for White and African-American mothers born <30 (compared to ≥37) weeks equaled 4.0 (1.2, 12.6) and 2.3 (1.2, 4.3), respectively. The adjusted OR of modestly early PTB for White and African-American mothers born 30–33 (compared to ≥37) weeks equaled 1.6 (1.0, 2.5) and 1.3 (0.9, 1.7), respectively. The adjusted OR of late PTB for White and African-American mothers born 34–36 (compared to ≥37) weeks equaled 1.2 (1.0, 1.3) and 1.1 (1.0, 1.2), respectively. Conclusions A generational association of extremely early, but not modestly early or late, PTB exists among non-Latino Whites and African-Americans.
Original language | English (US) |
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Pages (from-to) | 2061-2067 |
Number of pages | 7 |
Journal | Maternal and child health journal |
Volume | 21 |
Issue number | 11 |
DOIs | |
State | Published - Nov 1 2017 |
Funding
Acknowledgements This study was funded by research grants from the March of Dimes (12-FY04-45 and 12-FY09-159).
Keywords
- Extreme prematurity
- Preterm birth
- Race
- Transgenerational
ASJC Scopus subject areas
- Public Health, Environmental and Occupational Health
- Obstetrics and Gynecology
- Epidemiology
- Pediatrics, Perinatology, and Child Health