Early results with antegrade collagen injection for post-radical prostatectomy stress urinary incontinence

Carl G. Klutke*, Robert B. Nadler, Debbie Tiemann, Gerald L. Andriole

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

23 Scopus citations

Abstract

Purpose: Results of retrograde transurethral collagen injection for treatment of stress urinary incontinence have been generally disappointing for men with intrinsic sphincter deficiency following radical prostatectomy. We describe a new technique of antegrade transvesical collagen injection using suprapubic percutaneous bladder access. Materials and Methods: Between October 1994 and January 1996, 20 patients underwent antegrade collagen injection for post-radical prostatectomy stress urinary incontinence. Evaluation by pad test, urodynamics and subjective scores was performed before and after injection. Results: At a mean followup of 8.5 months 9 of 20 patients (45%) had significant subjective improvement and 5 (25%) were totally dry. Conclusions: Antegrade collagen injection is a promising and simple method of correcting post-radical prostatectomy stress urinary incontinence. Further study and longer followup are necessary to determine its precise role in the treatment of this condition.

Original languageEnglish (US)
Pages (from-to)1703-1706
Number of pages4
JournalJournal of Urology
Volume156
Issue number5
DOIs
StatePublished - Nov 1996

Keywords

  • collagen
  • prostate
  • prostatectomy
  • stress
  • urinary incontinence

ASJC Scopus subject areas

  • Urology

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