Effect of amino acids on renal tubular bicarbonate reabsorption by the rat kidney.

D. C. Battle*, Y. L. Chan

*Corresponding author for this work

Research output: Contribution to journalArticle

1 Scopus citations

Abstract

This study shows that L-arginine, a dibasic amino acid, which decreases in proximal convoluted tubule HCO3 transport, does not inhibit renal Na+/K+ ATPase activity or O2 consumption in vitro. Thus, a mechanism(s) other than inhibition of Na+/K ATPase likely accounts for the inhibitory effect of dibasic aminoacids on HCO3 transport in the superficial proximal convoluted tubule. Neutral and acid aminoacids, unlike dibasic aminoacids, do not inhibit HCO3 transport in this nephron segment.

Original languageEnglish (US)
Pages (from-to)173-183
Number of pages11
JournalProgress in clinical and biological research
Volume258
StatePublished - 1988

ASJC Scopus subject areas

  • Medicine(all)

Fingerprint Dive into the research topics of 'Effect of amino acids on renal tubular bicarbonate reabsorption by the rat kidney.'. Together they form a unique fingerprint.

  • Cite this