Effect of dietary sodium reduction on red blood cell sodium concentration and sodium-lithium countertransport

Richard Cooper*, Maurizio Trevisan, Linda Van Horn, Emmanuel Larbi, Kiang Liu, Seraphim Nanas, Hirotsugu Ueshima, Christopher Sempos, David Ostrow, Jeremiah Stamler

*Corresponding author for this work

Research output: Contribution to journalArticle

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A randomized, crossover trial was carried out on the effect of moderate sodium reduction on red-blood-cell sodium metabolism. The participants were healthy high school students (mean age = 16 years, n = 33). Changes in sodium-lithium countertransport and intracellular sodium concentration were evaluated 24 days after a decrease in dietary sodium from approximately 110 to 40 mEq per day. Dietary sodium restriction had no significant effect on either sodium-lithium countertransport or intracellular sodium concentration.

Original languageEnglish (US)
Pages (from-to)731-735
Number of pages5
Issue number5
StatePublished - Jan 1 1984



  • Blood pressure
  • Countertransport
  • Randomized trial
  • Sodium

ASJC Scopus subject areas

  • Internal Medicine

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