@inproceedings{1af33df07cf54bc8af68e38f206a95e0,
title = "Effect of high levels of film compression on surfactant transport",
abstract = "A previously developed adsorption-limited model that describes the transport of lung surfactant to and from an air-liquid interface has been extended to allow for diffusion in the bulk phase. We used this model to compare to experimental data from Schurch [1989]. We find that high levels of film compression lead transiently to large changes in adsorption rate, desorption rate and diffusion constant, consistent with what might expected if a selected purification of the interface was occurring leading to DPPC enrichment of the interface. The collapse of the surfactant film that occurs during compression leads to a significant elevation of surfactant concentration immediately underlying the interface, consistent with the formation of a subsurface depot of surfactant.",
author = "J. Morris and Ingenito, {E. P.} and L. Mark and Kamm, {R. D.} and M. Johnson",
year = "1999",
language = "English (US)",
isbn = "0780356756",
series = "Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings",
publisher = "IEEE",
pages = "356",
booktitle = "Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings",
note = "Proceedings of the 1999 IEEE Engineering in Medicine and Biology 21st Annual Conference and the 1999 Fall Meeting of the Biomedical Engineering Society (1st Joint BMES / EMBS) ; Conference date: 13-10-1999 Through 16-10-1999",
}