Effect of internal friction on biofilament dynamics

Michael G. Poirier*, John F. Marko

*Corresponding author for this work

Research output: Contribution to journalArticle

29 Scopus citations

Abstract

We consider biofilaments-flexible multimolecule structures common in cell biology-and show how "internal" friction associated with either conformational fluctuations or with fluid flow through narrow pores inside the filaments can dominate the external hydrodynamic friction usually considered to be the main energy dissipation process. The signature of this is wave-number-independent relaxation time of bending fluctuations. Preliminary experimental data for bending fluctuations of single folded (mitotic) chromosomes display these dynamics.

Original languageEnglish (US)
Number of pages1
JournalPhysical review letters
Volume88
Issue number22
StatePublished - Jun 3 2002

ASJC Scopus subject areas

  • Physics and Astronomy(all)

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