Abstract
OBJECTIVE: To determine the effect of methadone on the biophysical profile. STUDY DESIGN: Sixteen narcotics-dependent gravidas on methadone maintenance were selected for the study. Biophysical profiles and nonstress tests (NSTs) were performed on women between 28 and 40 weeks' estimated gestational are before and two hours after methadone was given. The reactivity of the nonstress tests, biophysical profile scores and time needed to complete the biophysical profile before and after methadone dosing were compared. RESULTS: Significantly more NSTs were nonreactive after methadone (P < .001), and it took more time for the NST to become reactive (P <.01). Although it took longer for the modified biophysical profile to be completed after methadone dosing, with the mean time going from 3.8 to 19.8 minutes (P <.01), the scores were the same before and lifter methadone in 75% of the women, with the mean score not significantly different before or after methadone. CONCLUSION: Our results suggest that the modified biophysical profile is a clinically useful test in the methadone-maintained gravida.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 819-822 |
| Number of pages | 4 |
| Journal | Journal of Reproductive Medicine for the Obstetrician and Gynecologist |
| Volume | 41 |
| Issue number | 11 |
| State | Published - Nov 1996 |
Funding
Keywords
- biophysical profile
- fetal movement
- methadone
ASJC Scopus subject areas
- Reproductive Medicine
- Obstetrics and Gynecology