Effect of Physical Activity on Self-Reported Disability in Older Adults

Results from the LIFE Study

the LIFE study investigators

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Background/Objectives: To test the hypothesis that a long-term structured, moderate intensity physical activity (PA) program is more effective than a health education (HE) program in reducing the risk of s elf-reported dependency and disability in basic activities of daily living (BADLs), disability in instrumental ADLs (IADL), and mobility disability. Design: The Lifestyle Interventions and Independence for Elders (LIFE) study was a multicenter, single-blinded randomized trial. Setting: University-based research clinic. Participants: Thousand six hundred and thirty five sedentary men and women aged 70–89 years, who had functional limitations, defined as a score ≤9 on the Short Physical Performance Battery. Intervention: Participants were randomized to a structured, moderate intensity PA program (n = 818) that included aerobic, resistance, and flexibility exercises or to a HE program (n = 817). Measurements: All outcomes were derived by self-report using periodic interviews that asked about the degree of difficulty and receipt of help during the past month. Dependency was defined as “receiving assistance” or “unable” to do ≥1 activities. Disability was defined as having “a lot of difficulty” or “unable” doing ≥1 activities. Severe disability was defined as reporting difficulty or being unable to perform ≥3 activities. Results: Over an average follow-up of 2.6 years, the cumulative incidence of BADL dependency was 15.2% among PA and 15.1% among HE participants (HR = 1.0, 95% CI = 0.78–0.1.3). Intervention groups had similar rates of incident BADL disability, IADL disability and reported mobility disability. Reporting severe mobility disability (HR = 0.78, 95% CI = 0.64–0.96) and ratings of difficulty on mobility tasks were reduced in the PA group. Conclusion: A structured physical activity intervention reduces reported severe mobility disability and difficulty on mobility tasks, but not BADL and IADL disability in older adults with functional limitations.

Original languageEnglish (US)
Pages (from-to)980-988
Number of pages9
JournalJournal of the American Geriatrics Society
Volume65
Issue number5
DOIs
StatePublished - May 1 2017

Fingerprint

Activities of Daily Living
Life Style
Exercise
Health Education
Self Report
Interviews
Incidence
Research
Dependency (Psychology)

Keywords

  • ambulation
  • exercise
  • frailty
  • rehabilitation

ASJC Scopus subject areas

  • Geriatrics and Gerontology

Cite this

@article{04fe9ef96f4e4693acae81a92fea2aac,
title = "Effect of Physical Activity on Self-Reported Disability in Older Adults: Results from the LIFE Study",
abstract = "Background/Objectives: To test the hypothesis that a long-term structured, moderate intensity physical activity (PA) program is more effective than a health education (HE) program in reducing the risk of s elf-reported dependency and disability in basic activities of daily living (BADLs), disability in instrumental ADLs (IADL), and mobility disability. Design: The Lifestyle Interventions and Independence for Elders (LIFE) study was a multicenter, single-blinded randomized trial. Setting: University-based research clinic. Participants: Thousand six hundred and thirty five sedentary men and women aged 70–89 years, who had functional limitations, defined as a score ≤9 on the Short Physical Performance Battery. Intervention: Participants were randomized to a structured, moderate intensity PA program (n = 818) that included aerobic, resistance, and flexibility exercises or to a HE program (n = 817). Measurements: All outcomes were derived by self-report using periodic interviews that asked about the degree of difficulty and receipt of help during the past month. Dependency was defined as “receiving assistance” or “unable” to do ≥1 activities. Disability was defined as having “a lot of difficulty” or “unable” doing ≥1 activities. Severe disability was defined as reporting difficulty or being unable to perform ≥3 activities. Results: Over an average follow-up of 2.6 years, the cumulative incidence of BADL dependency was 15.2{\%} among PA and 15.1{\%} among HE participants (HR = 1.0, 95{\%} CI = 0.78–0.1.3). Intervention groups had similar rates of incident BADL disability, IADL disability and reported mobility disability. Reporting severe mobility disability (HR = 0.78, 95{\%} CI = 0.64–0.96) and ratings of difficulty on mobility tasks were reduced in the PA group. Conclusion: A structured physical activity intervention reduces reported severe mobility disability and difficulty on mobility tasks, but not BADL and IADL disability in older adults with functional limitations.",
keywords = "ambulation, exercise, frailty, rehabilitation",
author = "{the LIFE study investigators} and Manini, {Todd M.} and Beavers, {Daniel P.} and Marco Pahor and Guralnik, {Jack M.} and Bonnie Spring and Church, {Timothy S.} and King, {Abby C.} and Folta, {Sara C.} and Glynn, {Nancy W.} and Marsh, {Anthony P.} and Gill, {Thomas M.}",
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pages = "980--988",
journal = "Journal of the American Geriatrics Society",
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Effect of Physical Activity on Self-Reported Disability in Older Adults : Results from the LIFE Study. / the LIFE study investigators.

In: Journal of the American Geriatrics Society, Vol. 65, No. 5, 01.05.2017, p. 980-988.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Effect of Physical Activity on Self-Reported Disability in Older Adults

T2 - Results from the LIFE Study

AU - the LIFE study investigators

AU - Manini, Todd M.

AU - Beavers, Daniel P.

AU - Pahor, Marco

AU - Guralnik, Jack M.

AU - Spring, Bonnie

AU - Church, Timothy S.

AU - King, Abby C.

AU - Folta, Sara C.

AU - Glynn, Nancy W.

AU - Marsh, Anthony P.

AU - Gill, Thomas M.

PY - 2017/5/1

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N2 - Background/Objectives: To test the hypothesis that a long-term structured, moderate intensity physical activity (PA) program is more effective than a health education (HE) program in reducing the risk of s elf-reported dependency and disability in basic activities of daily living (BADLs), disability in instrumental ADLs (IADL), and mobility disability. Design: The Lifestyle Interventions and Independence for Elders (LIFE) study was a multicenter, single-blinded randomized trial. Setting: University-based research clinic. Participants: Thousand six hundred and thirty five sedentary men and women aged 70–89 years, who had functional limitations, defined as a score ≤9 on the Short Physical Performance Battery. Intervention: Participants were randomized to a structured, moderate intensity PA program (n = 818) that included aerobic, resistance, and flexibility exercises or to a HE program (n = 817). Measurements: All outcomes were derived by self-report using periodic interviews that asked about the degree of difficulty and receipt of help during the past month. Dependency was defined as “receiving assistance” or “unable” to do ≥1 activities. Disability was defined as having “a lot of difficulty” or “unable” doing ≥1 activities. Severe disability was defined as reporting difficulty or being unable to perform ≥3 activities. Results: Over an average follow-up of 2.6 years, the cumulative incidence of BADL dependency was 15.2% among PA and 15.1% among HE participants (HR = 1.0, 95% CI = 0.78–0.1.3). Intervention groups had similar rates of incident BADL disability, IADL disability and reported mobility disability. Reporting severe mobility disability (HR = 0.78, 95% CI = 0.64–0.96) and ratings of difficulty on mobility tasks were reduced in the PA group. Conclusion: A structured physical activity intervention reduces reported severe mobility disability and difficulty on mobility tasks, but not BADL and IADL disability in older adults with functional limitations.

AB - Background/Objectives: To test the hypothesis that a long-term structured, moderate intensity physical activity (PA) program is more effective than a health education (HE) program in reducing the risk of s elf-reported dependency and disability in basic activities of daily living (BADLs), disability in instrumental ADLs (IADL), and mobility disability. Design: The Lifestyle Interventions and Independence for Elders (LIFE) study was a multicenter, single-blinded randomized trial. Setting: University-based research clinic. Participants: Thousand six hundred and thirty five sedentary men and women aged 70–89 years, who had functional limitations, defined as a score ≤9 on the Short Physical Performance Battery. Intervention: Participants were randomized to a structured, moderate intensity PA program (n = 818) that included aerobic, resistance, and flexibility exercises or to a HE program (n = 817). Measurements: All outcomes were derived by self-report using periodic interviews that asked about the degree of difficulty and receipt of help during the past month. Dependency was defined as “receiving assistance” or “unable” to do ≥1 activities. Disability was defined as having “a lot of difficulty” or “unable” doing ≥1 activities. Severe disability was defined as reporting difficulty or being unable to perform ≥3 activities. Results: Over an average follow-up of 2.6 years, the cumulative incidence of BADL dependency was 15.2% among PA and 15.1% among HE participants (HR = 1.0, 95% CI = 0.78–0.1.3). Intervention groups had similar rates of incident BADL disability, IADL disability and reported mobility disability. Reporting severe mobility disability (HR = 0.78, 95% CI = 0.64–0.96) and ratings of difficulty on mobility tasks were reduced in the PA group. Conclusion: A structured physical activity intervention reduces reported severe mobility disability and difficulty on mobility tasks, but not BADL and IADL disability in older adults with functional limitations.

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