Effect of piperoxane on rat plasma prolactin

H. Y. Meltzer*, R. G. Fessler, V. S. Fang

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

3 Scopus citations


There are conflicting results as to whether drugs which affect noradrenergic mechanisms affect rat prolactin secretion. Piperoxane, an α-adrenergic receptor blocker and clonidine, an α-adrenergic agonist, were found not to significantly affect prolactin secretion in male rats. The piperoxane results do not support a previous report which suggests this agent may have anti-psychotic action based on its ability to stimulate prolactin secretion in non-human primates.

Original languageEnglish (US)
Pages (from-to)237-242
Number of pages6
JournalCommunications In Psychopharmacology
Issue number3
StatePublished - Dec 1 1978

ASJC Scopus subject areas

  • General Medicine


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