Effect of testosterone on the hypothalamic-pituitary-gonadal axis of pinealectomized and pineal-intact male rats

E. P. Wallen; F. W. Turek

doi:10.1007/BF01960410

Effect of testosterone on the hypothalamic-pituitary-gonadal axis of pinealectomized and pineal-intact male rats

E. P. Wallen^*, F. W. Turek

^*Corresponding author for this work

Neurobiology

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Abstract

Previous studies indicate that steroid hormones alter pineal biochemistry, and it has been suggested that at least part of the negative feedback effect of steroid hormones on pituitary gonadotropin release may be mediated by the pineal gland. In this study, pinealectomy did not alter the inhibitory effect of testosterone on neuroendocrine-gonadal activity in the male rat, suggesting that the pineal gland does not mediate the response of the rat hypothalamic-pituitary axis to testosterone.

Original language	English (US)
Pages (from-to)	705-706
Number of pages	2
Journal	Experientia
Volume	35
Issue number	5
DOIs	https://doi.org/10.1007/BF01960410
State	Published - May 1979

ASJC Scopus subject areas

General Biochemistry, Genetics and Molecular Biology

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abstract = "Previous studies indicate that steroid hormones alter pineal biochemistry, and it has been suggested that at least part of the negative feedback effect of steroid hormones on pituitary gonadotropin release may be mediated by the pineal gland. In this study, pinealectomy did not alter the inhibitory effect of testosterone on neuroendocrine-gonadal activity in the male rat, suggesting that the pineal gland does not mediate the response of the rat hypothalamic-pituitary axis to testosterone.",

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Effect of testosterone on the hypothalamic-pituitary-gonadal axis of pinealectomized and pineal-intact male rats

Abstract

ASJC Scopus subject areas

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