Effect of the iChoose Kidney decision aid in improving knowledge about treatment options among transplant candidates

A randomized controlled trial

Rachel E. Patzer*, Laura McPherson, Mohua Basu, Sumit Mohan, Michael Wolf, Mariana Chiles, Allison Russell, Jennifer C. Gander, John J Friedewald, Daniela P Ladner, Christian P. Larsen, Thomas Pearson, Stephen Pastan

*Corresponding author for this work

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

We previously developed a mobile- and web-based decision aid (iChoose Kidney) that displays individualized risk estimates of survival and mortality, for the treatment modalities of dialysis versus kidney transplantation. We examined the effect of iChoose Kidney on change in transplant knowledge and access to transplant in a randomized controlled trial among patients presenting for evaluation in three transplant centers. A total of 470 patients were randomized to standard transplantation education (control) or standard education plus iChoose Kidney (intervention). Change in transplant knowledge (primary outcome) among intervention versus control patients was assessed using nine items in pre- and postevaluation surveys. Access to transplant (secondary outcome) was defined as a composite of waitlisting, living donor inquiries, or transplantation. Among 443 patients (n = 226 intervention; n = 216 control), the mean knowledge scores were 5.1 ± 2.1 pre- and 5.8 ± 1.9 postevaluation. Change in knowledge was greater among intervention (1.1 ± 2.0) versus control (0.4 ± 1.8) patients (P <.0001). Access to transplantation was similar among intervention (n = 168; 74.3%) versus control patients (n = 153; 70.5%; P =.37). The iChoose Kidney decision aid improved patient knowledge at evaluation, but did not impact transplant access. Future studies should examine whether combining iChoose Kidney with other interventions can increase transplantation. (Clinicaltrials.gov NCT02235571).

Original languageEnglish (US)
Pages (from-to)1954-1965
Number of pages12
JournalAmerican Journal of Transplantation
Volume18
Issue number8
DOIs
StatePublished - Aug 1 2018

Fingerprint

Decision Support Techniques
Randomized Controlled Trials
Transplants
Kidney
Transplantation
Therapeutics
Education
Living Donors
Kidney Transplantation
Dialysis
Survival
Mortality

Keywords

  • clinical research/practice
  • dialysis
  • education
  • health services and outcomes research
  • kidney disease
  • kidney transplantation/nephrology
  • patient education
  • patient survival

ASJC Scopus subject areas

  • Immunology and Allergy
  • Transplantation
  • Pharmacology (medical)

Cite this

Patzer, Rachel E. ; McPherson, Laura ; Basu, Mohua ; Mohan, Sumit ; Wolf, Michael ; Chiles, Mariana ; Russell, Allison ; Gander, Jennifer C. ; Friedewald, John J ; Ladner, Daniela P ; Larsen, Christian P. ; Pearson, Thomas ; Pastan, Stephen. / Effect of the iChoose Kidney decision aid in improving knowledge about treatment options among transplant candidates : A randomized controlled trial. In: American Journal of Transplantation. 2018 ; Vol. 18, No. 8. pp. 1954-1965.
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abstract = "We previously developed a mobile- and web-based decision aid (iChoose Kidney) that displays individualized risk estimates of survival and mortality, for the treatment modalities of dialysis versus kidney transplantation. We examined the effect of iChoose Kidney on change in transplant knowledge and access to transplant in a randomized controlled trial among patients presenting for evaluation in three transplant centers. A total of 470 patients were randomized to standard transplantation education (control) or standard education plus iChoose Kidney (intervention). Change in transplant knowledge (primary outcome) among intervention versus control patients was assessed using nine items in pre- and postevaluation surveys. Access to transplant (secondary outcome) was defined as a composite of waitlisting, living donor inquiries, or transplantation. Among 443 patients (n = 226 intervention; n = 216 control), the mean knowledge scores were 5.1 ± 2.1 pre- and 5.8 ± 1.9 postevaluation. Change in knowledge was greater among intervention (1.1 ± 2.0) versus control (0.4 ± 1.8) patients (P <.0001). Access to transplantation was similar among intervention (n = 168; 74.3{\%}) versus control patients (n = 153; 70.5{\%}; P =.37). The iChoose Kidney decision aid improved patient knowledge at evaluation, but did not impact transplant access. Future studies should examine whether combining iChoose Kidney with other interventions can increase transplantation. (Clinicaltrials.gov NCT02235571).",
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Effect of the iChoose Kidney decision aid in improving knowledge about treatment options among transplant candidates : A randomized controlled trial. / Patzer, Rachel E.; McPherson, Laura; Basu, Mohua; Mohan, Sumit; Wolf, Michael; Chiles, Mariana; Russell, Allison; Gander, Jennifer C.; Friedewald, John J; Ladner, Daniela P; Larsen, Christian P.; Pearson, Thomas; Pastan, Stephen.

In: American Journal of Transplantation, Vol. 18, No. 8, 01.08.2018, p. 1954-1965.

Research output: Contribution to journalArticle

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