Effect of TMP-SMX on nasopharyngeal carriage of ampicillin-sensitive and ampicillin-resistant Hemophilus influenzae type B

Ram Yogev*, Herman B. Lander, A. Todd Davis

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

33 Scopus citations

Abstract

The carriage rate of ampicillin-resistant Hemophilus influenzae type B in a chronic care facility was investigated. Up to 48% of the children carried this strain. Of interest was the finding of simultaneous carriage of ampicillin-resistant and ampicillin-sensitive HITB, a phenomenon which was detected by using both chocolate agar and chocolate agar containing 2 μg/ml of ampicillin. A trial of sulfamethoxazole-trimethoprim successfully eradicated the ampicillin-sensitive HITB, but had no effect on the ampicillin-resistant HITB.

Original languageEnglish (US)
Pages (from-to)394-397
Number of pages4
JournalJournal of Pediatrics
Volume93
Issue number3
DOIs
StatePublished - Jan 1 1978

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

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