Effect of TMP-SMX on nasopharyngeal carriage of ampicillin-sensitive and ampicillin-resistant Hemophilus influenzae type B

Ram Yogev; Herman B. Lander; A. Todd Davis

doi:10.1016/S0022-3476(78)81144-5

Effect of TMP-SMX on nasopharyngeal carriage of ampicillin-sensitive and ampicillin-resistant Hemophilus influenzae type B

Ram Yogev^*, Herman B. Lander, A. Todd Davis

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

34 Scopus citations

Abstract

The carriage rate of ampicillin-resistant Hemophilus influenzae type B in a chronic care facility was investigated. Up to 48% of the children carried this strain. Of interest was the finding of simultaneous carriage of ampicillin-resistant and ampicillin-sensitive HITB, a phenomenon which was detected by using both chocolate agar and chocolate agar containing 2 μg/ml of ampicillin. A trial of sulfamethoxazole-trimethoprim successfully eradicated the ampicillin-sensitive HITB, but had no effect on the ampicillin-resistant HITB.

Original language	English (US)
Pages (from-to)	394-397
Number of pages	4
Journal	Journal of Pediatrics
Volume	93
Issue number	3
DOIs	https://doi.org/10.1016/S0022-3476(78)81144-5
State	Published - Jan 1 1978
Externally published	Yes

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health

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10.1016/S0022-3476(78)81144-5

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title = "Effect of TMP-SMX on nasopharyngeal carriage of ampicillin-sensitive and ampicillin-resistant Hemophilus influenzae type B",

abstract = "The carriage rate of ampicillin-resistant Hemophilus influenzae type B in a chronic care facility was investigated. Up to 48% of the children carried this strain. Of interest was the finding of simultaneous carriage of ampicillin-resistant and ampicillin-sensitive HITB, a phenomenon which was detected by using both chocolate agar and chocolate agar containing 2 μg/ml of ampicillin. A trial of sulfamethoxazole-trimethoprim successfully eradicated the ampicillin-sensitive HITB, but had no effect on the ampicillin-resistant HITB.",

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AU - Lander, Herman B.

AU - Davis, A. Todd

PY - 1978/1/1

Y1 - 1978/1/1

N2 - The carriage rate of ampicillin-resistant Hemophilus influenzae type B in a chronic care facility was investigated. Up to 48% of the children carried this strain. Of interest was the finding of simultaneous carriage of ampicillin-resistant and ampicillin-sensitive HITB, a phenomenon which was detected by using both chocolate agar and chocolate agar containing 2 μg/ml of ampicillin. A trial of sulfamethoxazole-trimethoprim successfully eradicated the ampicillin-sensitive HITB, but had no effect on the ampicillin-resistant HITB.

AB - The carriage rate of ampicillin-resistant Hemophilus influenzae type B in a chronic care facility was investigated. Up to 48% of the children carried this strain. Of interest was the finding of simultaneous carriage of ampicillin-resistant and ampicillin-sensitive HITB, a phenomenon which was detected by using both chocolate agar and chocolate agar containing 2 μg/ml of ampicillin. A trial of sulfamethoxazole-trimethoprim successfully eradicated the ampicillin-sensitive HITB, but had no effect on the ampicillin-resistant HITB.

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Effect of TMP-SMX on nasopharyngeal carriage of ampicillin-sensitive and ampicillin-resistant Hemophilus influenzae type B

Abstract

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