Effects of childbearing on the natural history of panic disorder with comorbid mood disorder

Katherine L. Wisner*, Kathleen S. Peindl, Barbara H. Hanusa

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

50 Scopus citations

Abstract

This historical prospective study included 22 women with panic disorder. They experienced 45 pregnancies associated with or after their first lifetime episode of panic disorder. Mood disorder predated or was associated with 32 of these pregnancies. The most common effect of pregnancy was No Change in symptoms from baseline during pregnancy and continued No Change postnatally for both panic attacks (n = 22; 49%) and depression (n = 19; 59%). The pattern of panic attacks across gestations was consistent for only 5 of 14 multiparae. An interesting observation was that first lifetime onset of panic disorder was common postpartum (n = 4) or post-miscarriage (n = 2). First-onset depression was also common postpartum (n = 4).

Original languageEnglish (US)
Pages (from-to)173-180
Number of pages8
JournalJournal of Affective Disorders
Volume41
Issue number3
DOIs
StatePublished - Dec 16 1996

Keywords

  • depression
  • panic disorder
  • postpartum
  • pregnancy

ASJC Scopus subject areas

  • Clinical Psychology
  • Psychiatry and Mental health

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