Effects of dehydration on phonation in excised canine larynges

Jack Jiang*, Katherine Verdolini, Jennie Ng, Ben Aquino, David Hanson

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

71 Scopus citations


The effects of exposure to dry air on phonation were measured in an ex vivo model of vocal fold vibration. Excised canine larynges were mounted on an apparatus and made to phonate at a constant subglottal pressure by means of unhumidified airflow. The phonation threshold pressure (PTP), glottal airflow, sound intensity of the acoustic output, and effects on vocal efficiency were also assessed. Student's t-test was performed on the results. In 17 larynges, the average PTP increased from 10.0 cm H20 to 15.0 cm H2O after exposure to dry airflow (p < .001). In addition, the average flow increased from 585 mL/s to 801 mL/s at a constant suprathreshold subglottal pressure (p < .001), and from 323 mL/s to 610 mL/s at the PTP (p < .001). The average acoustic output levels, measured during stable phonation segments, markedly decreased with exposure to the dry airflow, from 91.5 dB to 88.5 dB (p < .001). The average vocal efficiency decreased from 3.63 x 10-4 to 7.00 x 10-5 (p < .001). No such changes were seen in control larynges phonated with 100% humidified air used for driving the airflow. The results support previously reported modeling and experimental findings that dehydration of the vocal fold generally degrades laryngeal performance.

Original languageEnglish (US)
Pages (from-to)568-575
Number of pages8
JournalAnnals of Otology, Rhinology and Laryngology
Issue number6
StatePublished - 2000


  • Canine
  • Dehydration
  • Excised larynx
  • Phonation
  • Phonation threshold pressure
  • Subglottal pressure
  • Vocal efficiency

ASJC Scopus subject areas

  • Otorhinolaryngology


Dive into the research topics of 'Effects of dehydration on phonation in excised canine larynges'. Together they form a unique fingerprint.

Cite this