Effects of selected growth factors on monolayer expansion of adult canine articular chondrocytes and subsequent growth in type II collagen- glycosaminoglycan matrices in vitro

R. M. Capito*, M. Spector

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

The effects of the selected growth factors on the proliferation and morphology of adult canine articular chondrocytes through monolayer expansion and subsequent growth in type II collagen-glycosaminoglycan (CG) matrices were investigated. It was found that there were notable differences in the monolayer growth comparing the fetal bovine serum (FBS) and FBS+three growth factors (3GF) media. It was observed that all pellets displayed intensive glycosaminoglycan (GAG) staining throughout with no discernable difference between the two groups. It was also observed that the cells expanded in monolayer in FBS+3GF produced more GAG and type II collagen in the CG matrices.

Original languageEnglish (US)
Title of host publicationTransactions - 7th World Biomaterials Congress
Number of pages1
StatePublished - Dec 1 2004
EventTransactions - 7th World Biomaterials Congress - Sydney, Australia
Duration: May 17 2004May 21 2004

Publication series

NameTransactions - 7th World Biomaterials Congress

Other

OtherTransactions - 7th World Biomaterials Congress
CountryAustralia
CitySydney
Period5/17/045/21/04

ASJC Scopus subject areas

  • Engineering(all)

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