Effects of sevoflurane anaesthesia on recovery in children: A comparison with halothane

Sanford L Lapin, Steve M. Auden*, L. Jane Goldsmith, Anne Marie Reynolds

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

163 Scopus citations


We prospectively studied one hundred ASA physical status I-II children, ages six months to six years, undergoing myringotomy surgery. Children were randomly assigned to one of four anaesthetic groups receiving either halothane or sevoflurane for anaesthesia and oral midazolam premedication or no premedication. We found that children anaesthetized with sevoflurane had significantly faster recovery times and discharge home times than those who received halothane. Patients given oral midazolam premedication had significantly longer recovery times, but no delay in discharge home compared with those not premedicated. However, children anaesthetized with sevoflurane and no premedication had an unacceptably high incidence (67%) of postoperative agitation. The use of oral midazolam preoperatively did decrease the amount of postoperative agitation seen with sevoflurane. We conclude that although sevoflurane does shorten recovery times, the degree of associated postoperative agitation makes it unacceptable as a sole anaesthetic for myringotomy surgery.

Original languageEnglish (US)
Pages (from-to)299-304
Number of pages6
JournalPaediatric anaesthesia
Issue number4
StatePublished - 1999


  • Postoperative agitation
  • Recovery time
  • Sevoflurane: oral midazolam

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Anesthesiology and Pain Medicine

Fingerprint Dive into the research topics of 'Effects of sevoflurane anaesthesia on recovery in children: A comparison with halothane'. Together they form a unique fingerprint.

Cite this