Effects of xerostomia on perception and performance of swallow function

Jeri A. Logemann*, Christina H. Smith, Barbara Roa Pauloski, Alfred W. Rademaker, Cathy L. Lazarus, Laura A. Colangelo, Bharat Mittal, Ellen MacCracken, Joy Gaziano, Linda Stachowiak, Lisa A. Newman

*Corresponding author for this work

Research output: Contribution to journalArticle

94 Scopus citations

Abstract

Background. Head and neck cancer treatment with high-dose chemoradiation may cause xerostomia and affect the patient's perception of swallowing ability. Method. Whole saliva production was measured in 36 patients with advanced-stage cancer of the oropharynx before treatment and 3 months after treatment by weighing a 4 × 4 inch gauze before and after a 2-minute chewing period. Presence of multiple eating difficulties was measured by patient interview. Swallowing was examined videofluorographically (VFG). Results. Saliva weight decreased from a mean (SEM) of 5.1 (0.5) g pretreatment to 1.4 (0.5) g after treatment (p < .0001). At 3 months, significantly more patients perceived difficulty swallowing, dry mouth, needing water while eating, food stuck in the mouth or throat, and change in taste. Saliva weight was not correlated with VFG measures of bolus transit or observations of residue. Conclusions. Chemoradiation treatment results in xerostomia and a significant increase in patient perception of swallowing difficulties. Saliva weight in patients who perceive swallowing problems was lower. Xerostomia did not affect the physiologic aspects of bolus transport. Xerostomia affected the sensory process and comfort of eating more than bolus transport.

Original languageEnglish (US)
Pages (from-to)317-321
Number of pages5
JournalHead and Neck
Volume23
Issue number4
DOIs
StatePublished - 2001

Keywords

  • Dysphagia
  • Stimulated saliva production
  • Swallowing
  • Videofluorography
  • Xerostomia

ASJC Scopus subject areas

  • Otorhinolaryngology

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    Logemann, J. A., Smith, C. H., Pauloski, B. R., Rademaker, A. W., Lazarus, C. L., Colangelo, L. A., Mittal, B., MacCracken, E., Gaziano, J., Stachowiak, L., & Newman, L. A. (2001). Effects of xerostomia on perception and performance of swallow function. Head and Neck, 23(4), 317-321. https://doi.org/10.1002/hed.1037