Efficacy of Analgesic Treatments to Manage Children's Postoperative Pain After Laparoscopic Appendectomy: Retrospective Medical Record Review

Renee C B Manworren, Connor D. McElligott, Peter V. Deraska, James Santanelli, Sherry Blair, Kimberly A. Ruscher, Richard Weiss, Christine Rader, Christine Finck, Michael Bourque, Brendan Campbell

Research output: Contribution to journalArticle

8 Scopus citations

Abstract

Knowledge of the effectiveness of multimodal analgesic treatments to manage children's postoperative pain during hospital stays is limited. Our retrospective chart review of a convenience sample of 200 pediatric surgical patients' pain experiences during the first 24 hours after laparoscopic appendectomy demonstrates the benefits of a multimodal analgesic approach. We found that pediatric patients who received perioperative IV ketorolac in addition to opioids reported statistically significantly lower mean pain intensity (n = 134, mean [M] = 2.9, standard deviation [SD] = 1.7) during the first 24 hours after surgery when compared with the pain intensity of patients who did not receive perioperative IV ketorolac (n = 66, M = 3.7, SD = 1.7, t = 3.14, P = .002). Patients who received perioperative IV ketorolac (M = 0.94, SD = 0.71) also received significantly fewer morphine equivalents of postoperative opioids during the first 24 hours after surgery than those who did not (M = 1.21, SD = 0.78, t = 2.41, P = .02). We will use data from these patients to introduce the potential for a personalized medicine approach to postoperative pain.

Original languageEnglish (US)
Pages (from-to)317.e1-317.e11
JournalAORN journal
Volume103
Issue number3
DOIs
StatePublished - Mar 1 2016

Keywords

  • IV ketorolac
  • Laparoscopic appendectomy
  • Pediatric analgesia
  • Pediatric pain
  • Postoperative pain management

ASJC Scopus subject areas

  • Medical–Surgical

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    Manworren, R. C. B., McElligott, C. D., Deraska, P. V., Santanelli, J., Blair, S., Ruscher, K. A., Weiss, R., Rader, C., Finck, C., Bourque, M., & Campbell, B. (2016). Efficacy of Analgesic Treatments to Manage Children's Postoperative Pain After Laparoscopic Appendectomy: Retrospective Medical Record Review. AORN journal, 103(3), 317.e1-317.e11. https://doi.org/10.1016/j.aorn.2016.01.013