Efficacy of LAIV-T on Absentee Rates in a School-Based Health Center Sample

Cynthia J. Mears*, Elisa N. Lawler, Lee D. Sanders, Ben Z. Katz

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

15 Scopus citations


Purpose: To determine the effectiveness of the intranasal LAIV-T in decreasing school absenteeism in a school-based vaccination initiative and to compare the acceptability of LAIV-T versus TIV among adolescents. Methods: This study was conducted within a single, urban community high school in the Fall of 2006. Participation was offered to all students in grades 6 to 10, aged 11 to 17 years. In December, school health center staff administered influenza vaccines to the students whose parents had returned written consent. Students received LAIV-T (n = 86), unless they were medically ineligible or objected; in those cases the injectable inactivated trivalent influenza vaccine (TIV) (n = 41) was offered. Students that did not receive either vaccination served as a control group (n = 234). Nonsuspension absences between January and June of 2007 were tracked for all three groups. Results: Students who received the LAIV-T had significantly less nonsuspension absences (mean absences = 5.53, SD = 5.00) compared to both the TIV (mean absences = 9.45, SD = 9.07) and control groups (mean absences = 7.97, SD =7.59). Conclusions: LAIV-T was associated with a reduction in nonsuspension absences and was well accepted by students. Administration of LAIV-T may be a convenient and effective method to mass-immunize students in a school setting and help establish herd immunity within the community.

Original languageEnglish (US)
Pages (from-to)91-94
Number of pages4
JournalJournal of Adolescent Health
Issue number1
StatePublished - Jul 2009


  • Adolescent
  • Herd immunity
  • Inactivated trivalent influenze vaccine
  • Live-attenuated intranasal influenza vaccine trivalent
  • School-based health center

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Public Health, Environmental and Occupational Health
  • Psychiatry and Mental health


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