Efficacy of pharmacological therapies for the treatment of opioid-induced constipation: Systematic review and meta-analysis

Keyphrases

• Meta-analysis 100%
• Systematic Meta-analysis 100%
• Pharmacological Therapy 100%
• Opioid-induced Constipation 100%
• Relative Risk 83%
• Randomized Controlled Trial 83%
• Confidence Interval 83%
• Lubiprostone 66%
• Patient Relatives 50%
• Opioid Antagonist 50%
• Prucalopride 50%
• Failure Risk 33%
• Placebo 33%
• Active Therapy 33%
• Embase 33%
• Responder Rate 33%
• Failure to Respond 33%
• High Responder 33%
• Response to Therapy 16%
• Placebo-controlled Trial 16%
• Adverse Events 16%
• Duration of Therapy 16%
• Analgesia 16%
• Diarrhea 16%
• MEDLINE 16%
• Naloxone 16%
• Abdominal Pain 16%
• Random Effects Model 16%
• Cochrane Central Register of Controlled Trials 16%
• Methylnaltrexone 16%
• Linaclotide 16%
• Alvimopan 16%

Pharmacology, Toxicology and Pharmaceutical Science

• Pharmacotherapy 100%
• Constipation 100%
• Randomized Controlled Trial 83%
• Lubiprostone 66%
• Placebo 50%
• Prucalopride 50%
• Narcotic Antagonist 50%
• Naloxone 16%
• Methylnaltrexone 16%
• Random Effects Model 16%
• Alvimopan 16%
• Adverse Event 16%
• Diarrhea 16%
• Abdominal Pain 16%
• Linaclotide 16%