Efficient algorithm for optimization of multibed adiabatic reactor sequence

Marshall D. Rafal, Joshua S. Dranoff

Research output: Contribution to journalArticlepeer-review


The problem of optimizing the design of a sequence of adiabatic packed-bed reactors has been reviewed, and a practical and efficient digital computation algorithm for the solution of this problem has been developed. Based on a combination of analytic criteria for the optimum and a dynamic programming formulation, this algorithm becomes highly efficient as the number of reactors increases-reaching an effective upper limit in the significant computations required after about five stages. The application of this approach to a realistic system, the water-gas shift reaction, is illustrated.

Original languageEnglish (US)
Pages (from-to)129-135
Number of pages7
JournalIndustrial and Engineering Chemistry Process Design and Development
Issue number2
StatePublished - Apr 1 1966

ASJC Scopus subject areas

  • Chemistry(all)
  • Chemical Engineering(all)
  • Engineering(all)
  • Industrial and Manufacturing Engineering


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