Efficient generation of cycle time-throughput curves through simulation and metamodeling

Feng Yang, Bruce E Ankenman*, Barry L Nelson

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

44 Scopus citations


A cycle time-throughput (CT-TH) curve, which quantifies the relationship of long-run average cycle time to throughput rate, plays an important role in strategic planning for manufacturing systems. In this paper, a nonlinear regression metamodel supported by queueing theory is developed to represent the underlying CT-TH curve implied by a manufacturing simulation model. To estimate the model efficiently, simulation experiments are built up sequentially using a multistage procedure. Extensive numerical experiments are presented to demonstrate the effectiveness of the proposed procedure.

Original languageEnglish (US)
Pages (from-to)78-93
Number of pages16
JournalNaval Research Logistics
Issue number1
StatePublished - Feb 1 2007


  • Design of experiments
  • Discrete event simulation
  • Queueing
  • Response surface modeling
  • Semiconductor manufacturing

ASJC Scopus subject areas

  • Modeling and Simulation
  • Ocean Engineering
  • Management Science and Operations Research


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