Efficient recognition-induced acceleration of a [3+2] dipolar cycloaddition reaction

Ceri A. Booth, Douglas Philp*

*Corresponding author for this work

Research output: Contribution to journalArticle

24 Scopus citations

Abstract

The rational design of a system which is capable of utilising molecular recognition between an amidopyridine and a carboxylic acid to accelerate the [3+2] dipolar cycloaddition reaction between an azide and a maleimide is presented.

Original languageEnglish (US)
Pages (from-to)6987-6990
Number of pages4
JournalTetrahedron Letters
Volume39
Issue number38
DOIs
StatePublished - Sep 17 1998

Keywords

  • Azides
  • Cycloadditions
  • Kinetics
  • Molecular recognition

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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