Electrocardiogram changes as predictors for new imaging findings in repeat transthoracic echocardiography

Anis John Kadado*, Abdullah Pervaiz, Kyle Gobeil, Saima Shikari, Petal Elder, Ayman Battisha, Ritika Walia, William Hiser, Tara Lagu, Quinn R. Pack

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

Aim: To determine if electrocardiogram (EKG) findings may be a useful tool to predict changes in repeat transthoracic echocardiogram (TTE). Methods: We evaluated patients who underwent TTE during hospitalization and their EKGs, and whether findings differed between studies. Results: Of 229 hospitalized patients who underwent repeat TTE, 183 (80%) were abnormal. Each minor and major EKG abnormality resulted in a 1.8 (1.2 to 2.6; p = 0.002) and 2.1 (1.3 to 3.3; p < 0.001) increased odds of abnormal imaging on TTE, respectively. The negative likelihood ratio for an unchanged EKG to predict an unchanged TTE was 0.68 (95% CI = 0.62 to 0.73). Conclusion: Among hospitalized patients with prior imaging results, an unchanged EKG predicts an unchanged TTE.

Original languageEnglish (US)
Pages (from-to)487-495
Number of pages9
JournalFuture Cardiology
Volume19
Issue number10
DOIs
StatePublished - Aug 1 2023

Funding

QR Pack is supported by grants from the National Heart, Lung and Blood Institute of the National Institutes of Health, under Award Number 1K23HL135440. T Lagu is supported by the National Heart, Lung and Blood Institute of the National Institutes of Health under Awards 1R01HL146884-01 and R01 HL139985-01A1. This work was also funded by RedCap (UL1RR025752, UL1TR000073, UL1TR001064 and UL1TR002544) through Tufts. The authors have no other relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript apart from those disclosed.

Keywords

  • cardiac imaging
  • cardiomyopathies
  • echocardiography
  • electrophysiology
  • imaging

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Molecular Medicine

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