Electromagnetic fields low levels altered the DNA infrared region in RA-differentiated SH-SY5Y neuroblastoma cells

Emanuele Calabrò*, Salvatore Condello, Salvatore Magazù, Riccardo Ientile

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

Differentiated neuroblastoma cells (SH-SY5Y) were used to study the effects of lowstatic magnetic fields (SMFs) and extremely low frequency electromagnetic fields (ELF-EMFs) on the structure of DNA. Fourier Transform Infrared (FTIR) spectroscopy analysis showed that exposures to a SMF at 2mT and to a 50Hz EMF at 0.7mT produced peak's centroid shift and significant decreases of the phosphate absorption bands in the infrared region of DNA. The exposure also induced significant increase in reactive oxygen species (ROS) production in comparison to control confirming this scenario.

Original languageEnglish (US)
Pages (from-to)267-271
Number of pages5
JournalBioTechnology: An Indian Journal
Volume6
Issue number8-9
StatePublished - Dec 1 2012

Keywords

  • DNA
  • Electromagnetic fields
  • FTIR spectroscopy
  • Reactive oxygen species
  • SH-SY5Y neuroblastoma cells

ASJC Scopus subject areas

  • Biotechnology
  • Food Science
  • Biochemistry

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