Electronic detection of the enzymatic degradation of starch

Alexander Star; Vikram Joshi; Tzong Ru Han; M. Virginia P Altoé; George Grüner; J. Fraser Stoddart

doi:10.1021/ol0495826

Electronic detection of the enzymatic degradation of starch

Alexander Star^*, Vikram Joshi, Tzong Ru Han, M. Virginia P Altoé, George Grüner, J. Fraser Stoddart

^*Corresponding author for this work

Chemistry

Research output: Contribution to journal › Article › peer-review

53 Scopus citations

Abstract

The enzymatic degradation of starch can be monitored electronically using single-walled carbon nanotubes (SWNTs) as semiconducting probes in field-effect transistors (FETs). Incubation of these devices in aqueous buffer solutions of amyloglucosidase (AMG) results in the removal of the starch from both the silicon surfaces and the side walls of the SWNTs in the FETs, as evidenced by direct imaging and electronic measurements.

Original language	English (US)
Pages (from-to)	2089-2092
Number of pages	4
Journal	Organic Letters
Volume	6
Issue number	13
DOIs	https://doi.org/10.1021/ol0495826
State	Published - Jun 24 2004

ASJC Scopus subject areas

Biochemistry
Physical and Theoretical Chemistry
Organic Chemistry

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abstract = "The enzymatic degradation of starch can be monitored electronically using single-walled carbon nanotubes (SWNTs) as semiconducting probes in field-effect transistors (FETs). Incubation of these devices in aqueous buffer solutions of amyloglucosidase (AMG) results in the removal of the starch from both the silicon surfaces and the side walls of the SWNTs in the FETs, as evidenced by direct imaging and electronic measurements.",

author = "Alexander Star and Vikram Joshi and Han, {Tzong Ru} and Alto{\'e}, {M. Virginia P} and George Gr{\"u}ner and Stoddart, {J. Fraser}",

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AU - Joshi, Vikram

AU - Han, Tzong Ru

AU - Altoé, M. Virginia P

AU - Grüner, George

AU - Stoddart, J. Fraser

PY - 2004/6/24

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N2 - The enzymatic degradation of starch can be monitored electronically using single-walled carbon nanotubes (SWNTs) as semiconducting probes in field-effect transistors (FETs). Incubation of these devices in aqueous buffer solutions of amyloglucosidase (AMG) results in the removal of the starch from both the silicon surfaces and the side walls of the SWNTs in the FETs, as evidenced by direct imaging and electronic measurements.

AB - The enzymatic degradation of starch can be monitored electronically using single-walled carbon nanotubes (SWNTs) as semiconducting probes in field-effect transistors (FETs). Incubation of these devices in aqueous buffer solutions of amyloglucosidase (AMG) results in the removal of the starch from both the silicon surfaces and the side walls of the SWNTs in the FETs, as evidenced by direct imaging and electronic measurements.

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