Electrospinning bioactive supramolecular polymers from water

Alok S. Tayi, E. Thomas Pashuck, Christina J. Newcomb, Mark T. McClendon, Samuel I. Stupp*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

44 Scopus citations


Electrospinning is a high-throughput, low-cost technique for manufacturing long fibers from solution. Conventionally, this technique is used with covalent polymers with large molecular weights. We report here the electrospinning of functional peptide-based supramolecular polymers from water at very low concentrations (<4 wt %). Molecules with low molecular weights (<1 kDa) could be electrospun because they self-assembled into one-dimensional supramolecular polymers upon solvation and the critical parameters of viscosity, solution conductivity, and surface tension were optimized for this technique. The supramolecular structure of the electrospun fibers could ensure that certain residues, like bioepitopes, are displayed on the surface even after processing. This system provides an opportunity to electrospin bioactive supramolecular materials from water for biomedical applications.

Original languageEnglish (US)
Pages (from-to)1323-1327
Number of pages5
Issue number4
StatePublished - Apr 14 2014

ASJC Scopus subject areas

  • Bioengineering
  • Biomaterials
  • Polymers and Plastics
  • Materials Chemistry


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