Elemental analysis using differential absorption techniques

H. Rarback; F. Cinotti; C. Jacobsen; J. M. Kenney; J. Kirz; R. Rosser

doi:10.1007/BF02796625

Elemental analysis using differential absorption techniques

H. Rarback^*, F. Cinotti, C. Jacobsen, J. M. Kenney, J. Kirz, R. Rosser

^*Corresponding author for this work

Physics and Astronomy

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Abstract

X-ray differential absorption microanalysis is presented as a technique for trace element analysis of hydrated biological specimens of about 0.1-5 μm thickness. For the study of the light elements (Z≲20), the absorption technique minimizes the radiation dose and, thus, damage to such specimens when compared with X-ray fluorescence. A Scanning Transmission X-ray Microscope (SXTM) is described, which has been used to map the concentration of calcium in bone with better than 300 nm spatial resolution and a sensitivity to 5% calcium by weight. Future plans are briefly discussed that offer the hope of achieving 0.1% trace element sensitivity and 75 nm spatial resolution.

Original language	English (US)
Pages (from-to)	103-113
Number of pages	11
Journal	Biological Trace Element Research
Volume	13
Issue number	1
DOIs	https://doi.org/10.1007/BF02796625
State	Published - Aug 1 1987

Keywords

X-ray absorption microanalysis
X-ray microscopy
biological microanalysis
bone
calcium distribution

ASJC Scopus subject areas

Endocrinology, Diabetes and Metabolism
Biochemistry
Clinical Biochemistry
Inorganic Chemistry
Biochemistry, medical

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1007/BF02796625

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abstract = "X-ray differential absorption microanalysis is presented as a technique for trace element analysis of hydrated biological specimens of about 0.1-5 μm thickness. For the study of the light elements (Z≲20), the absorption technique minimizes the radiation dose and, thus, damage to such specimens when compared with X-ray fluorescence. A Scanning Transmission X-ray Microscope (SXTM) is described, which has been used to map the concentration of calcium in bone with better than 300 nm spatial resolution and a sensitivity to 5% calcium by weight. Future plans are briefly discussed that offer the hope of achieving 0.1% trace element sensitivity and 75 nm spatial resolution.",

keywords = "X-ray absorption microanalysis, X-ray microscopy, biological microanalysis, bone, calcium distribution",

author = "H. Rarback and F. Cinotti and C. Jacobsen and Kenney, {J. M.} and J. Kirz and R. Rosser",

year = "1987",

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T1 - Elemental analysis using differential absorption techniques

AU - Rarback, H.

AU - Cinotti, F.

AU - Jacobsen, C.

AU - Kenney, J. M.

AU - Kirz, J.

AU - Rosser, R.

PY - 1987/8/1

Y1 - 1987/8/1

N2 - X-ray differential absorption microanalysis is presented as a technique for trace element analysis of hydrated biological specimens of about 0.1-5 μm thickness. For the study of the light elements (Z≲20), the absorption technique minimizes the radiation dose and, thus, damage to such specimens when compared with X-ray fluorescence. A Scanning Transmission X-ray Microscope (SXTM) is described, which has been used to map the concentration of calcium in bone with better than 300 nm spatial resolution and a sensitivity to 5% calcium by weight. Future plans are briefly discussed that offer the hope of achieving 0.1% trace element sensitivity and 75 nm spatial resolution.

AB - X-ray differential absorption microanalysis is presented as a technique for trace element analysis of hydrated biological specimens of about 0.1-5 μm thickness. For the study of the light elements (Z≲20), the absorption technique minimizes the radiation dose and, thus, damage to such specimens when compared with X-ray fluorescence. A Scanning Transmission X-ray Microscope (SXTM) is described, which has been used to map the concentration of calcium in bone with better than 300 nm spatial resolution and a sensitivity to 5% calcium by weight. Future plans are briefly discussed that offer the hope of achieving 0.1% trace element sensitivity and 75 nm spatial resolution.

KW - X-ray absorption microanalysis

KW - X-ray microscopy

KW - biological microanalysis

KW - bone

KW - calcium distribution

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Elemental analysis using differential absorption techniques

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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