Elevated plasma concentrations of β-thromboglobulin were observed in 25 consecutive patients with chronic renal failure. Further increases in this platelet protein were observed during hemodialysis but not during peritoneal dialysis. The hemodialysis-induced increases were not prevented by either aspirin or dipyridamole, a fact which suggested that release of this protein was not dependent on platelet functional activity. Measurement of β-thromboglobulin provides a sensitive indicator of platelet disruption during hemodialysis.
|Original language||English (US)|
|Number of pages||7|
|Journal||The Journal of laboratory and clinical medicine|
|State||Published - May 1980|
ASJC Scopus subject areas
- Pathology and Forensic Medicine