Elevated β-thromboglobulin in patients with chronic renal failure: effect of hemodialysis

David Green*, S. Santhanam, F. A. Krumlovsky, F. del Greco

*Corresponding author for this work

Research output: Contribution to journalArticle

31 Scopus citations

Abstract

Elevated plasma concentrations of β-thromboglobulin were observed in 25 consecutive patients with chronic renal failure. Further increases in this platelet protein were observed during hemodialysis but not during peritoneal dialysis. The hemodialysis-induced increases were not prevented by either aspirin or dipyridamole, a fact which suggested that release of this protein was not dependent on platelet functional activity. Measurement of β-thromboglobulin provides a sensitive indicator of platelet disruption during hemodialysis.

Original languageEnglish (US)
Pages (from-to)679-685
Number of pages7
JournalThe Journal of laboratory and clinical medicine
Volume95
Issue number5
StatePublished - May 1980

ASJC Scopus subject areas

  • Pathology and Forensic Medicine

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