Elevated rate of 3H-uridine incorporation in regressing rat ventral prostate

T. Stanisic, R. Sadlowski, C. Lee, J. T. Grayhack

Research output: Contribution to journalArticlepeer-review

4 Scopus citations


Ventral prostates from adult Sprague-Dawley rats were removed at intervals during the first 2 weeks postcastration. Incubation of tissue with 3H-uridine and 3H-leucine was performed to determine the incorporation rate of radioactivity into the RNA and protein fractions respectively. Prostatic wet weight and 3H-leucine incorporation rate into prostate protein diminished postcastration, whereas 3H-uridine incorporation rate remained relatively high. The data suggest that RNA synthesis is relatively active in comparison with other parameters during regression.

Original languageEnglish (US)
Pages (from-to)15-18
Number of pages4
JournalInvestigative urology
Issue number1
StatePublished - Jan 1 1978

ASJC Scopus subject areas

  • Medicine(all)

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