Elucidating the substrate specificity and condensation domain activity of FkbP, the FK520 pipecolate-incorporating enzyme

Keyphrases

• Substrate Specificity 100%
• Pipecolate 100%
• FK520 100%
• Condensation Domain 100%
• Acetylation 66%
• Polyketide Synthase 66%
• Nonribosomal Peptide Synthetase 66%
• Recombinant 33%
• Site-directed mutagenesis 33%
• Pipecolic Acid 33%
• Biosynthetic Pathway 33%
• Transfer Reactions 33%
• Protein Domain 33%
• Rapp Model 33%
• Amino Acid Substitution 33%
• Natural Products 33%
• Rapamycin 33%
• Polyketides 33%
• Macrocycles 33%
• Functional Elements 33%
• Acyl Chain 33%
• Selectivity Filter 33%
• FK506 33%
• Acyl Carrier Protein 33%
• Proline 33%
• Fourier Transform Mass Spectrometry 33%
• Adenylation Domain 33%
• Streptomycetes 33%
• Peptidyl Carrier Protein 33%
• Aminoacyl 33%
• Radioassay 33%
• Hybrid Polyketide 33%

Biochemistry, Genetics and Molecular Biology

• Acetylation 100%
• Enzyme 100%
• Enzyme Specificity 100%
• Nonribosomal Peptide 100%
• Polyketide Synthase 100%
• Copurification 50%
• N-Terminus 50%
• Adenylylation 50%
• Anabolism 50%
• Amino Acids 50%
• Mass Spectrometry 50%
• Site-Directed Mutagenesis 50%
• Polyketide 50%
• Streptomycetaceae 50%
• Acyl Carrier Protein 50%
• Mitochondrial Membrane Transport Protein 50%
• Carrier Protein 50%
• Proline 50%