Molecular dynamics simulations of single crystal nickel were performed to analyze the influence of specimen size on ductile fracture. Uniaxial tension of four specimen sizes ranging from approximately 5,000 atoms to 170,000 atoms with the same initial void volume fraction was performed at high rates of deformation (108 - 1010/sec). The 3D specimens were given a rectangular initial shape with uniform thickness and were provided with one and two cylindrical voids. Parameters quantifying damage evolution such as, post-initial yielding stress-strain behavior and void volume fraction evolution were computed as the voids grew and coalesced due to the increasing applied tractions. The results showed that the different specimen size changes the dislocation pattern, the void aspect ratio, and the stress-strain response of the specimens. From zero to 20% strain the void growth is dominated by dislocation nucleation that correlates with the size scale influence observed by Horstemeyer et al. . Beyond 20% the size scale differences cease to be relevant because the effects of dislocation nucleation are overcome by dislocation interaction. This study provides the fodder for development of continuum damage mechanics phenomenological models for use in nanocrystalline materials.