Emergence of risk factors in children

Darwin R. Labarthe*

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingChapter


This chapter discusses the 'emergence' of risk factors for atherosclerotic and hypertensive diseases in children and adolescents. The emergence of cardiovascular risk factors in childhood and adolescence is characterized in general by (a) a progressive shift in risk factor distributions with increasing age toward undesirable levels; (b) a tendency for clustering of multiple factors within individual persons; (c) tracking of risk factor values at the higher-risk extreme; and (d) an association with the extent and severity of atherosclerotic lesions observed well before adulthood. Variation in the trajectories of change in mean values of specific risk factors - such as distinct components of blood lipids, blood pressure, or blood glucose and insulin concentrations - indicates some complexity in these patterns and suggests that they may differ in some important aspects of causation and prevention.

Original languageEnglish (US)
Title of host publicationCoronary Heart Disease Epidemiology
Subtitle of host publicationFrom Aetiology to Public Health
PublisherOxford University Press
ISBN (Electronic)9780191724114
ISBN (Print)9780198525738
StatePublished - Sep 1 2009


  • Cardiovascular disease
  • Children's health
  • Clustering
  • Coronary heart disease
  • Risk factor distributions

ASJC Scopus subject areas

  • Psychology(all)


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