Emerging and re-emerging infectious diseases: the third epidemiologic transition

R. Barrett*, C. W. Kuzawa, T. McDade, G. J. Armelagos, W.H. Durham (Editor)

*Corresponding author for this work

Research output: Book/ReportBook

73 Scopus citations


We use an expanded framework of multiple epidemiologic transitions to review the issues of re/emerging infection. The first epidemiologic transitiion was associated with a rise in infectious diseases that accompanied the Neolithic Revolution. The second epidemiologic transition involved the shift from infectious to chronic disease mortality associated with industrialization. The recent resurgence of infectious disease mortality marks a third epidemiologic transition characterized by newly emerging, re-emerging, and antibiotic resistant pathogens in the context of an accelerated globalization of human disease ecologies. These transitions illustrate recurring sociohistorical and ecological themes in human-disease relationships from the Paleolithic Age to the present day.

Original languageEnglish (US)
PublisherAnnual Reviews Inc
Number of pages25
StatePublished - Dec 1 1998

ASJC Scopus subject areas

  • General Earth and Planetary Sciences
  • General Environmental Science


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